Hello,
I’ve been building a tool with AI assistance that generates cancer genomic reports from structured patient data. A sample report is attached.
It produces two versions from the same input:
- Clinician view: VAF, mutation frequency, evidence-level treatments, resistance flags, mutational signatures
- Patient view: plain language, no jargon
I’ve been using the FoundationOne CDx report from Foundation Medicine (as distributed by Chugai Pharma in Japan) as a reference for what a comprehensive genomic report should contain. Comparing against it, my current prototype is missing a few things I’d like to add: a Report Highlights summary section, pertinent negatives (important findings not detected), treatment benefit split by tumour type vs. other tumour types, and NCCN/NICE category of evidence alongside the OncoKB evidence levels.
Before going further, I’d love to know whether something like this is actually needed in NHS genomics workflows, or whether it duplicates something that already exists.
A few honest questions:
- Do NHS genomic labs currently produce a separate patient-facing report, or does the clinical report go to both the oncologist and patient as-is?
- Is the patient-facing layer something labs want but don’t have time to build?
- Would a lightweight open-source tool that plugs into existing assay output (VCF / lab JSON) and EHR data (FHIR) be useful, or is the integration overhead the real blocker?
I’m at the prototype stage — not a product, not validated, not a medical device. Just trying to make sure I’m solving a real problem before going further.
If anyone here works in NHS genomics, oncology, or a Genomic Medicine Centre — or knows someone who does — I’d really welcome a conversation. Feel free to reply here or message me directly.
Thanks
